Solid Tumor Clinical Trials in Birmingham, Alabama

20 recruitingBirmingham, Alabama

Showing 120 of 20 trials

Recruiting
Phase 1Phase 2

A First-in-human Study to Learn How Safe BAY 3713372 is and How it Works in Participants With MTAP-deleted Solid Tumors

MTAP-deleted Solid Tumors
Bayer370 enrolled60 locationsNCT06914128
Recruiting
Phase 1

A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors

Advanced Solid Tumor
BeOne Medicines105 enrolled16 locationsNCT07226349
Recruiting
Phase 1

An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors

Breast CancerAdvanced Solid Tumor
BeOne Medicines86 enrolled20 locationsNCT07222267
Recruiting
Phase 3

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

Solid Tumors
Incyte Corporation588 enrolled212 locationsNCT07522073
Recruiting
Phase 1Phase 2

Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

Advanced Solid Tumor
OncoC4, Inc.387 enrolled19 locationsNCT06635785
Recruiting
Phase 2

A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

Advanced Solid TumorsHER2 Mutation
Bayer111 enrolled54 locationsNCT06760819
Recruiting
Phase 1

A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors

Advanced Solid TumorAdvanced Breast CancerAdvanced Ovarian Cancer
Bristol-Myers Squibb234 enrolled21 locationsNCT06997029
Recruiting
Phase 1

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7566802 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Metastatic Solid TumorsLocally Advanced Solid TumorsRecurrent Solid Tumors
Genentech, Inc.250 enrolled18 locationsNCT06031441
Recruiting
Phase 2

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

Advanced Solid TumorsMultiple MyelomaLymphoma, Non-Hodgkin
American Society of Clinical Oncology4,200 enrolled174 locationsNCT02693535
Recruiting
Phase 1

A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

Solid TumorsClear Cell Renal Cell Carcinoma
Arcus Biosciences, Inc.362 enrolled29 locationsNCT05536141
Recruiting
Phase 1Phase 2

A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

Solid Tumor
Novartis Pharmaceuticals222 enrolled37 locationsNCT04939610
Recruiting
Phase 2

Trial Investigating Visugromab and Nivolumab With or Without Docetaxel in 2L Treatment of Participants With Metastatic NSCLC

Metastatic Non-Squamous Non-Small Cell Lung CancerAdult Solid Tumor
CatalYm GmbH131 enrolled13 locationsNCT07246863
Recruiting
Phase 1

TLN-372 in Advanced KRAS Mutant Solid Tumors

KRAS Mutant Solid Tumors
Treeline Biosciences, Inc.240 enrolled10 locationsNCT07204340
Recruiting
Phase 2

Trial Investigating Visugromab in Combination With Immunochemotherapy in 1L Treatment of Participants With Metastatic NSCLC

Metastatic Non-Squamous Non-Small Cell Lung CancerAdult Solid Tumor
CatalYm GmbH107 enrolled25 locationsNCT07098988
Recruiting
Phase 1Phase 2

A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002)

Advanced Solid TumorsMalignant Neoplasm
Merck Sharp & Dohme LLC270 enrolled42 locationsNCT06818643
Recruiting
Phase 1Phase 2

A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

Solid Tumor, Adult
Corbus Pharmaceuticals Inc.348 enrolled41 locationsNCT06265727
Recruiting

Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies

Solid TumorLeukemiaHematopoietic Cell Transplantation Recipient
Children's Oncology Group5,000 enrolled164 locationsNCT00736749
Recruiting
Phase 1

DCSZ11 as a Monotherapy and in Combination in Patients With Advanced or Metastatic Solid Tumors

Advanced or Metastatic Solid Tumors
DynamiCure Biotechnology320 enrolled35 locationsNCT05785754
Recruiting
Phase 1Phase 2

First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor.

Solid Tumor
Corbus Pharmaceuticals Inc.156 enrolled26 locationsNCT06603844
Recruiting
Phase 1

Safety, Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced Malignancies

Metastatic Solid TumorAdvanced Unresectable Solid Tumor
TopAlliance Biosciences499 enrolled24 locationsNCT04137900