Albuterol for Acute Lung Injury
lung recruitment maneuver with and without nebulized albuterol for acute lung injury, randomized controlled study
south valley university
50 participants
Jul 20, 2013
Interventional
Conditions
Summary
the study will test the value of adding aerosolized albuterol to lung recruitment during mechanical ventilation of patients with ALI to improve alveolar fluid clearance and oxygenation
Eligibility
Inclusion Criteria1
- patients with acute lung injury due to surgical and non surgical causes
Exclusion Criteria1
- hemodynamic instability , patients on b-blockers therapy
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Interventions
we will test the value of adding aerosolized albuterol sulphate 5mg dissolved in 10 ml sterile saline and nebulised by connecting the nebulizer to the endotracheal tube during mechanical ventilation of patients with acute lung injury (ALI) together with lung recruitment maneuver which is done in the form of increasing the positive end expiratory pressure (PEEP) 10 cm H2O above the lower infliction point for 15 minutes or 10 cmH2O above the pre-recruitment PEEP to be repeated every four hours for five to seven successive days in a trial to improve alveolar fluid clearance and improve oxygenation in these patients
Locations(1)
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ACTRN12613000836730