RecruitingNCT01808937

Morphea in Adults and Children (MAC) Cohort Study: A Morphea Registry and DNA Repository

Immunologic and Genetic Profiles in Subsets of Morphea Patients


Sponsor

University of Texas Southwestern Medical Center

Enrollment

500 participants

Start Date

May 1, 2007

Study Type

OBSERVATIONAL

Conditions

Summary

The Morphea in Adults and Children (MAC) cohort is the first registry for both children and adults with morphea (also known as localized scleroderma) in the country. The purpose of the registry is to learn more about morphea, specifically: * How morphea behaves over time * How frequently specific problems occur along with morphea (for example, arthritis) * Whether morphea has an autoimmune background


Eligibility

Max Age: 90 Years

Inclusion Criteria8

  • Patient must have a clinical diagnosis of morphea confirmed by the primary investigator and by histopathological examination.
  • Ages 0-90 years old
  • Children must weigh more than 20 lbs. in order to satisfy Children's Medical Center policy for the maximum amount of blood drawn in a 24 hour period.
  • Patient or legal guardian must be able to speak and read at a 6th grade reading level.
  • Both male and female patients will be eligible
  • All races and ethnic backgrounds will be included
  • Relationships to proband: All patients with morphea will be included. A patient's family history will be reviewed and if there is a family history of morphea or systemic sclerosis then we will give the study patient the investigator's contact information and ask the family member to call the study team to answer any questions and enroll them in the study if they choose to do so.
  • Ability to give informed consent: Patients must be able to give informed consent or they will give assent with parent or guardian consent as a minor to be a part of the morphea registry.

Exclusion Criteria1

  • \- Patients who have been coded as morphea (701.0), but do not have morphea/localized scleroderma (examples: steroid atrophy, acquired keratoderma, keloids, nephrogenic fibrosing dermopathy, systemic sclerosis, lichen sclerosis)

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Interventions

OTHERMorphea

Locations(1)

UT Southwestern Medical Center - Department of Dermatology

Dallas, Texas, United States

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