Advanced MR Imaging as Predictor of Treatment Response in Newly Diagnosed Glioblastomas

This study is looking at whether advanced brain scan (MRI) techniques can predict how well a newly diagnosed brain tumor (glioblastoma) will respond to standard treatment with radiation and chemotherapy. **You may be eligible if...** - You have been newly diagnosed with glioblastoma (a type of brain tumor), confirmed by both imaging and a tissue sample - Your tumor is still visible and measurable on an MRI scan - You are expected to live for more than 3 months - You are scheduled for the standard treatment: 6 weeks of radiation therapy plus a chemotherapy drug called temozolomide - You are able to sign a consent form (or a legal guardian can do so on your behalf) **You may NOT be eligible if...** - Your surgeon completely removed the entire tumor - No measurable tumor remains after surgery - You have already had chemotherapy or radiation therapy - You have a device implanted in your body that is activated electronically or magnetically, such as a pacemaker, cochlear implant, or nerve stimulator - You are pregnant or breastfeeding - Your post-surgery MRI images are too distorted to read clearly Talk to your doctor to see if this trial is right for you.