Trial of Curcumin to Prevent Progression of Low-risk Prostate Cancer Under Active Surveillance

This trial is testing whether taking curcumin (a natural compound found in turmeric) can slow the growth of low-risk prostate cancer in men who are being closely monitored rather than immediately treated — a strategy called "active surveillance." **You may be eligible if...** - You are between 40 and 89 years old - You have low-risk, localized prostate cancer confirmed by biopsy (at least 8 cores taken) - Your biopsy may have been done within the last 12 months - No more than 4 separate areas of your prostate show cancer **You may NOT be eligible if...** - You have intermediate- or high-risk prostate cancer - You have already received treatment for prostate cancer (surgery, radiation, or hormone therapy) - You have certain health conditions that prevent you from taking curcumin supplements safely - You have allergies to curcumin or turmeric products Talk to your doctor to see if this trial is right for you.