Noninvasive Elastography Evaluation of Myocardial Stiffness in Elderly Patients With Isolated Diastolic Heart Failure: New Diagnostic Tool?
French Cardiology Society
90 participants
Jan 24, 2020
INTERVENTIONAL
Conditions
Summary
The new approach propose in this protocol is based on ultrafast ultrasound and remote palpation of tissue by ultrasonic radiation pressure. Ultrafast ultrasound of biological tissues is based on an innovative ultrasound imaging approach that can image very fast soft tissue events at a rate of several thousands of frames per second and provide quantitative mapping of the elasticity of the tissues. This current project aims is to focus on myocardial rigidity in diastole to better assess the function of the heart failure.
Eligibility
Inclusion Criteria6
- Hospitalization in cardiology services for acute pulmonary edema during heart failure
- Natriuretic peptide type B ≥35 pg/ml
- Echocardiographic structural alteration
- Group "preserved LVEF": Left ventricular Ejection Fraction ≥50%
- Group "moderate alteration of LVEF": Left ventricular Ejection Fraction between 40% and 49%
- Group "Systolic heart failure": Left ventricular Ejection Fraction\< 40%
Exclusion Criteria5
- Other associated lung pathology
- Other heart disease
- Contraindication to MRI or echocardiography gel
- Pregnancy
- Poor echogenicity,
Interventions
3 examen performed assessed to compared evaluation type: Cardiac magnetic resonance imaging, standard ultrasound imaging and ultrafast imaging
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT03895541