Peritoneal Ultrafiltration in Cardio Renal Syndrome.

This study is looking at whether a treatment called peritoneal ultrafiltration — using the lining of the belly to remove excess fluid — can help people with severe heart and kidney failure who no longer respond well to water pills (diuretics). **You may be eligible if...** - You are 18 or older - You have severe heart failure with significant fluid overload despite maximum medication - Your heart's pumping function is reduced (ejection fraction 60% or less) - You are in NYHA Class III or IV heart failure — meaning significant symptoms even at rest or with minimal activity - You have signs of right-sided heart failure and resistance to diuretics - You have had right heart catheterization confirming these findings **You may NOT be eligible if...** - Your kidneys are functioning normally and you do not have fluid overload - You do not have the specific pattern of heart-kidney failure this study targets - You are not on maximum guideline-directed heart failure medications Talk to your doctor to see if this trial is right for you.