RecruitingNCT04115774

Registry of Osteogenesis Imperfecta

Registry of Osteogenesis Imperfecta That Collects Clinical, Functional, Genetic, Genealogical, Imaging, Surgical, Quality of Life Data. Data is Linked to Patients Biological Samples, When Available


Sponsor

Luca Sangiorgi

Enrollment

5,000 participants

Start Date

Jun 28, 2013

Study Type

OBSERVATIONAL

Conditions

Summary

ROI is a retrospective and prospective registry, finalized for care and research purposes. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains: personal information, clinical data, genetic data, genealogical data, surgeries, etc. This approach has been developed to corroborate and integrate data from different sources evaluating several aspects of diseases and to correlate genetic background and phenotypic outcomes, in order to better investigate diseases pathophysiology. Due to legal requirements, institutional directives and organizational issues, we are unable to include individuals residing outside Italy in the registry at this time. We are currently engaged in the preparation of a recruitment process for individuals residing outside Italy.


Eligibility

Inclusion Criteria1

  • All Osteogenesis Imperfecta patients, including prenatal and fetal diagnosis of Osteogenesis Imperfecta

Exclusion Criteria1

  • Any condition unrelated to Osteogenesis Imperfecta

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Interventions

DRUGbisphosphonates

Since this is an observational study, the investigators collect general information on bisphosphonates treatment/impact


Locations(1)

Irccs Istituto Ortopedico Rizzoli

Bologna, Emilia-Romagna, Italy

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NCT04115774


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