Prospective Longitudinal Observational Research in Atopic Dermatitis
Prospective Longitudinal Observational Research Study to Investigate the Remission of Atopic Dermatitis and Associated Allergic Diseases
University of Zurich
1,000 participants
Apr 4, 2017
OBSERVATIONAL
Conditions
Summary
Atopic dermatitis (AD) is a frequent chronic relapsing inflammatory skin disorder, characterized by intensely itchy eczema. AD usually starts within the first 2 years of life. In 30 - 60% of children, inflammation spreads onto other body surfaces such as the gastrointestinal tract, the respiratory tract, and the conjunctives within a few years. This sequence is called atopic march. Atopic dermatitis and associated atopic diseases are more frequent in families, suggesting a genetic predisposition. However, the underlying factors such as genetic phenotype, environmental factors, or life style which cause or worsen an existing allergic disease are not understood yet. Affected people suffer from recurrent flares that result in significantly impaired quality. This study will collect clinical and laboratory data to elucidate immunotolerance and preventiv stategies with the aim to develop new and individual treatment options of atopic diseases.
Eligibility
Inclusion Criteria7
- Age 0 - 85 years
- Diagnosis of AD and/or another disease of the atopic group (i.e. allergic rhinitis, allergic asthma, food allergy)
- The inclusion of patients in this study is independent from the current therapy. During the study all patients will be kept on a therapy that is medically indicated
- Age 0 - 85 years
- No diagnosis or history of allergic disease
- The inclusion of patients in this study is independent from the current therapy. During the study all patients will be kept on a therapy that is medically indicated
- Written consent will be obtained after detailed information of the study was given to the participant.
Exclusion Criteria1
- \- Unable to give consent or refusal to participate in the study
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04240522