RecruitingNCT04699292

International Prospective Registry on Local Treatment Approaches in MLS

International Prospective Registry on Local Treatment Approaches in Myxoid Liposarcomas


Sponsor

The Netherlands Cancer Institute

Enrollment

300 participants

Start Date

Jan 18, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

To prospectively study commonly used local treatment approaches in Myxoid Liposarcoma (MLS)


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Age \> 18 years
  • Biopsy proven MLS, including the reciprocal chromosomal translocation t(12;16)(q13;p11)
  • ECOG PS 0-2
  • Written informed consent to share coded information in this international Registry

Exclusion Criteria2

  • Prior radiotherapy to the target area
  • Pregnancy

Interventions

PROCEDURESurgery

Surgery

RADIATIONPreoperative RT 36Gy

Preoperative radiotherapy to 36Gy (equivalent)

RADIATIONPreoperative RT 50Gy

Preoperative radiotherapy to 50Gy (equivalent)

RADIATIONPostoperative RT 50-66Gy

Postoperative radiotherapy to 50-66Gy (equivalent)

RADIATIONRT 36Gy

Definitive radiotherapy to 36Gy (equivalent)


Locations(1)

The Netherlands Cancer Institute

Amsterdam, Netherlands

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NCT04699292


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