Evaluating the Impact of 18F-FDG-PET-CT on Risk Stratification and Treatment Adaptation for Patients with Muscle Invasive Bladder Cancer

This study evaluates whether using a special full-body PET-CT scan (with a radioactive sugar called FDG) helps doctors better plan treatment for patients with muscle-invasive bladder cancer — a form of bladder cancer that has grown into the muscle wall. **You may be eligible if:** - You are over 18 years old - You have been diagnosed with muscle-invasive bladder cancer confirmed by biopsy - You are planned for radical (curative) treatment - You are willing to undergo the FDG-PET-CT scan - You do not have distant metastases on standard imaging **You may NOT be eligible if:** - Your imaging already shows distant spread (metastases) - You have had prior bladder radiation - You are unwilling to undergo additional therapy (such as targeted treatment or immunotherapy) if the scan reveals spread - You have contraindications to the PET-CT scan - You have had another primary cancer within the last 5 years (with some exceptions) Talk to your doctor to see if this trial is right for you.