Long-term of Remote Ischemic Preconditioning in Patients With Mild Hypertension
Henan Institute of Cardiovascular Epidemiology
90 participants
Jul 3, 2021
INTERVENTIONAL
Conditions
Summary
According to the latest survey data of China hypertension annual meeting, there are about 300 million patients with hypertension in China, with 10 million new cases of hypertension each year, and there is an obvious trend of younger people. In particular, young and middle-aged people are in a state of mild hypertension for a long time, which causes great pressure on health and medical treatment. At present, the main clinical measures for mild hypertension are to change their eating habits, quit smoking and alcohol, exercise and other lifestyle changes, as well as drug control. For most patients with mild hypertension, drug control is not the best choice. It has been reported that remote ischemic preconditioning (RIPC) may play an effective role in reducing blood pressure .The purpose of this study was to investigate the extent of long-term application of RIPC to reduce blood pressure in patients with mild hypertension.
Eligibility
Inclusion Criteria1
- Diagnosed patients with mild hypertension (SBP: 140\~159mmHg; DBP: 90\~99mmHg)
Exclusion Criteria4
- Cannot tolerate RIPC
- Non-essential hypertension
- patients who have uncontrolled severe arrhythmia, diabetes, electrolyte disturbance
- patients who have severe organic diseases such acute myocardial infarction, cardiac insufficiency, abnormal renal function, etc.
Interventions
One of ACEI / ARB, beta blocker, calcium channel blocker, diuretic
40 minutes per day, 10 minutes as a cycle (cuff inflated to 200 mmHg and maintained for 5 minutes, then deflated for 5 minutes to start the next cycle)， a total of 4 cycles.
Such as changing dietary habits, smoking cessation and alcohol restriction, exercise and so on.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04753840