Antiseptic Effects on the Dental Implant Internal Surface Microbiome
Madigan Army Medical Center
150 participants
Jul 28, 2022
INTERVENTIONAL
Summary
Soldiers operate in environments that are more likely to lead to oral trauma, risking poor dentition which can directly impact military readiness. Dental restoration can often be accomplished via dental implant insertion. Microbiome-associated complications that result in bone loss, including the micro-leakage of bacterial species proliferating in the dental implant internal cavity, frequently lead to implant failure. Reduction in implant bacterial load may result in a shift of the composition of the microbiome in favor of less pathogenic species, potentially improving dental implant success rates, reducing surgical revisions, and associated cost savings. This study aims to determine how disinfectant gel (hydrogen peroxide or chlorhexidine) insertion into dental implant internal cavities affects implant failure rates, bacterial load and microbiome composition.
Eligibility
Inclusion Criteria3
- Active duty military
- -55 years old
- Over 6 months remaining at local duty station
Exclusion Criteria4
- Tobacco user
- Medications that affect soft tissue or bone healing
- Metabolic disorder that affects soft tissue or bone healing
- Active periodontal disease
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Interventions
Chlorhexidine will be inserted into the dental implant internal cavity during dental implant insertion.
Hydrogen Peroxide will be inserted into the internal cavity of the dental implant during dental implant insertion.
Locations(1)
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NCT05024760