RecruitingNot ApplicableNCT05296421

Investigating Targetable Metabolic Pathways Sustaining Pancreatic Cancer

Pilot Study to Investigate Targetable Metabolic Pathways Sustaining Pancreatic Cancer and Associated Genomic Alterations

Sponsor

Rutgers, The State University of New Jersey

Enrollment

16 participants

Start Date

Mar 14, 2022

Study Type

INTERVENTIONAL

Conditions

Pancreatic Ductal Adenocarcinoma

Summary

This clinical trial investigates the nutrients pancreatic cancers depend on in which to survive and the processes these tumors use (metabolism) to obtain these nutrients. Giving U-13C-glucose during surgery may allow doctors to trace the metabolic activity of pancreatic cancer in research experiments done in the laboratory. These experiments may help researchers understand how cancer cells manage their nutrients when compared to normal pancreatic cells.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study examines the metabolic (energy-processing) activity in pancreatic cancer cells to identify possible targets for new treatments. It collects tumor and normal tissue samples during surgery from patients undergoing an operation to remove their pancreatic cancer. **You may be eligible if...** - You are 18 or older - You have been diagnosed with pancreatic adenocarcinoma (a type of pancreatic cancer) by biopsy - You are scheduled for surgery to remove the cancer (with or without prior chemotherapy) - You are willing to have extra tissue samples taken during surgery for research - You are either newly diagnosed (no prior treatment) or have received at least 3 months of chemotherapy before surgery **You may NOT be eligible if...** - You are currently receiving other anti-cancer therapy (not part of this study) - Your tumor cannot be surgically removed - You are unable or unwilling to provide informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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