RecruitingNot ApplicableNCT05333367
MORPHEE : Mechanisms of Cell Death Induced by Extracorporeal Photochemotherapy
Sponsor
Centre Hospitalier Universitaire de Besancon
Enrollment
20 participants
Start Date
Apr 15, 2022
Study Type
INTERVENTIONAL
Conditions
Summary
The objective of this study is to describe the type of cell death induced by extracorporeal photochemotherapy, depending on the cell type, using a panel of complementary analysis techniques.
Eligibility
Min Age: 18 YearsMax Age: 85 Years
Inclusion Criteria2
- Adult patients
- Treated with ECP for at least 1 month, for control of GVHD in hematopoietic cell allograft (acute or chronic GVHD), treatment and control of cellular or humoral rejection in solid organ transplantation (heart, lung, kidney) or in the treatment of cutaneous T-cell lymphoma
Exclusion Criteria5
- Subjects with limited legal capacity.
- Subjects judged by the investigator to be unlikely to comply with study procedures
- Subjects with no social security coverage.
- Pregnant women.
- Subjects still in the exclusion period of another study, or according to the national registry of clinical trial participants.
Interventions
OTHERSamples collection
Sampling of 2 samples on the extracorporeal photochemotherapy circuit, before and after sensitization with 8-MOP and UVA irradiation (without additional puncture)
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05333367
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