RecruitingNot ApplicableNCT05333367

MORPHEE : Mechanisms of Cell Death Induced by Extracorporeal Photochemotherapy


Sponsor

Centre Hospitalier Universitaire de Besancon

Enrollment

20 participants

Start Date

Apr 15, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of this study is to describe the type of cell death induced by extracorporeal photochemotherapy, depending on the cell type, using a panel of complementary analysis techniques.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study (MORPHEE) is examining the biological mechanisms by which extracorporeal photochemotherapy (ECP) — a light-based treatment where blood is treated outside the body — causes cancer cells and overactive immune cells to die, to better understand and improve the therapy. **You may be eligible if...** - You are an adult who has been receiving ECP therapy for at least 1 month - You are being treated with ECP for graft-versus-host disease (GVHD) after a transplant, rejection after a solid organ transplant, or a type of skin cancer called cutaneous T-cell lymphoma **You may NOT be eligible if...** - You have limited legal capacity - You are unlikely to follow the study procedures in the investigator's judgment - You have no social security coverage - You are pregnant - You are currently excluded from another trial Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERSamples collection

Sampling of 2 samples on the extracorporeal photochemotherapy circuit, before and after sensitization with 8-MOP and UVA irradiation (without additional puncture)


Locations(1)

Centre Hospitalier Universitaire de Besançon

Besançon, France

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NCT05333367


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