RecruitingNot ApplicableNCT05380414

Profiling Program of Advanced/Metastatic Pancreatic Cancer Patients

A Single-center, Prospective Profiling Program of Advanced/Metastatic Pancreatic Cancer Patients


Sponsor

Centre Leon Berard

Enrollment

750 participants

Start Date

Jul 1, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The proposal is to implement a molecular screening program for advanced/metastatic pancreatic cancer patients before the initiation of 1st line treatment in order to allow a better selection of patients for rationale personalized medicine with targeted agents and/or combination involving a chemotherapy backbone.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is collecting detailed genetic and molecular information from patients with advanced or metastatic pancreatic cancer to better understand what drives tumor growth and to identify potential new treatment targets. **You may be eligible if...** - You are over 18 with confirmed advanced or metastatic pancreatic ductal adenocarcinoma (PDAC) - You have received no more than one prior chemotherapy treatment for metastatic disease - Tumor tissue (from surgery or biopsy) is available for testing - You have a life expectancy of more than 3 months - You are in good overall health (performance status 0 or 1) **You may NOT be eligible if...** - A curative treatment option is still available to you - You cannot safely provide blood samples - You have another active cancer that is growing or being treated Talk to your doctor to see if this trial is right for you.

This is a simplified summary. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALTumor samples (archival FFPE and optional de novo biopsy) and blood samples

Molecular screening


Locations(1)

Centre Léon Bérard

Lyon, France

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NCT05380414


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