RecruitingPhase 2NCT05441813

Coconut Oil to Prevent Mouth Sores in Pediatric Patients Receiving High Dose Chemotherapy

A Randomized, Open-label Study of Coconut Oil Mouth Rinse for Prophylaxis of Severe Oral Mucositis in Pediatric Patients Receiving Myeloablative Conditioning Regimens


Sponsor

Wake Forest University Health Sciences

Enrollment

60 participants

Start Date

Feb 15, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to learn if virgin coconut oil (VCO) mouth rinse can help prevent oral mucositis. The Study Investigator will compare standard of care mucositis prevention rinses with the VCO mouth rinse added to the standard of care mucositis prevention rinses. The severity of oral mucositis between the 2 groups will be evaluated. Some of the standard of care rinses that can be used to prevent mucositis are normal saline, Benadryl (diphenhydramine), Mylanta, lidocaine, or other combinations.


Eligibility

Min Age: 7 YearsMax Age: 26 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Virgin Coconut Oil for people with oral mucositis. The study is currently recruiting participants at 1 location. People eligible for this study include aged 7 Years to 26 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGVirgin Coconut Oil

Standard of care with the addition of virgin coconut oil mouth rinse


Locations(1)

Atrium Health Levine Children's Hospital

Charlotte, North Carolina, United States

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NCT05441813


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