RecruitingNCT05570929
LONGitudinal Multi-omics Phenotyping of KIDney Function Alteration
Observation of Alterations in Kidney Function, Immune System and Gut Mircobiota After Living Donor Kidney Transplantation
Sponsor
Charite University, Berlin, Germany
Enrollment
20 participants
Start Date
Feb 7, 2023
Study Type
OBSERVATIONAL
Conditions
Summary
This is a longitudinal observation of kidney function, immune system and gut microbiota before and 24 weeks after a live kidney transplantation conducted in donor and recipient pairs living in the same household. Outcome measures include kidney function, body composition, blood pressure, gut microbiome composition, metabolomics and immune cell states.
Eligibility
Min Age: 18 YearsMax Age: 75 Years
Inclusion Criteria2
- Body-Mass-Index 18,5 - 34,9 kg/m2
- Planned living kidney donation / transplantation
Exclusion Criteria6
- Clinically relevant heart, lung, liver, and kidney diseases
- Postoperative phase
- Acute infections
- Vegan diet
- Change of body weight of more than 10% in the month prior to study entry
- Known drug or alcohol abuse
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05570929
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