RecruitingNot ApplicableNCT05669443

Effect of Optimized PEEP on Mechanical Ventilation During Robot Assisted Laparoscopic Prostatectomy

Application of Individualized Positive End-expiratory Pressure Using Electrical Impedance Tomography (EIT) in Patients Undergoing Robot Assisted Laparoscopic Prostatectomy : a Randomized Controlled Study


Sponsor

Gangnam Severance Hospital

Enrollment

42 participants

Start Date

Apr 3, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Steep trendelenburg posture or pneumoperitoneum for surgery causes ventilation problems during surgery, so finding a way to overcome is a challenging task for anesthesiologists. In this study, for patients undergoing robot assisted laparoscopic prostatectomy under general anesthesia, anesthesia is going to perform by applying conventional positive end-expiratory pressure (PEEP 5cmH2O) or individually determined positive end-expiratory pressure values for each patient using electrical impedance tomography. We plan to compare intraoperative ventilation through arterial blood gas analysis to find out the way to improve intraoperative ventilation.


Eligibility

Sex: MALEMin Age: 20 YearsMax Age: 70 Years

Inclusion Criteria3

  • years of age who are scheduled for robotic assisted laparoscopic prostatectomy at the Department of Urology, Gangnam Severance Hospital,
  • ASA-PS (American Society of Anesthesiology Body Rating) I-IlI,
  • Patients with a BMI of 35 kg/m2 or less

Exclusion Criteria4

  • Patients with lung disease
  • BMI \>35kg/m2
  • Patients for whom positive end-tidal pressure cannot be applied (large bullae, severe cardiac disease)
  • patient refusal

Interventions

DEVICEconventional PEEP

Maintain positive end expiratory pressure at 5 cmH2O throughout the surgery.

DEVICEoptimized PEEP

Immediately after induction of anesthesia, the patient remains unapplied to PEEP. After pneumoperitoneum + Trendelenburg posture, an appropriate PEEP value is derived using electrical impedance tomography (airtom®). And then derived value ( = optimized PEEP value) is applied until the end of the operation.


Locations(1)

Gangnam Severacne Hospital Yonsei University College of Medicine

Seoul, South Korea

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NCT05669443


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