RecruitingPhase 4NCT05758701

CT TAVR Abdomen Study

Dual Energy CT Decreased IV Contrast Dose Imaging for TAVR


Sponsor

University of Maryland, Baltimore

Enrollment

164 participants

Start Date

Sep 19, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

A standard polyenergetic CT (computed tomography) procedure utilizes 100 ml of iodinated contrast. A recent world-wide shortage of iodine based intravenous contrast has highlighted the need to search for alternative methods or doses. Reducing iodinated IV contrast dose can mitigate IV contrast supply shortages and enable significant cost savings for the radiology practice and hospital system. In addition, decreased IV contrast dose can potentially reduce the rate of acute kidney injury, specifically in patients with decreased renal function. The purpose of the study is to determine whether low IV contrast dose CT with monoenergetic reconstruction can be use for presurgical planning of transcatheter valve replacement (TAVR) procedure.


Eligibility

Min Age: 18 YearsMax Age: 88 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Dual Energy CT and Iodinated Contrast Agent (Omnipaque) for people with transcatheter aortic valve replacement. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 88 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

COMBINATION_PRODUCTIodinated Contrast Agent (Omnipaque)

Standard dosage of Omnipaque for CT imaging is 100 ml. Cohort will be given a reduced dosage.

DEVICEDual Energy CT

Dual energy CT scanners enable monoenergetic CT image reconstruction which allows for improved iodine image contrast.


Locations(1)

University of Maryland Medical Center

Baltimore, Maryland, United States

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NCT05758701


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