Lung Tumor Protein Synthesis Rates in Lung Cancer Patients
Characterizing Tissue Protein Synthesis Rates of Non-small Cell Lung Carcinomas in Lung Cancer Patients
Maastricht University Medical Center
30 participants
Mar 1, 2023
OBSERVATIONAL
Conditions
Summary
The current study will recruit lung cancer patients to measure tissue protein synthesis rates of non-small cell lung carcinomas and healthy lung tissue. The protein synthesis rates of healthy lung tissue will be compared to lung tumor tissue to establish the remodeling characteristics of healthy versus cancerous lung tissues. We will also examine whether tissue protein synthesis rates of non-small cell lung carcinomas are associated with various tumor- (i.e., size, subclassification) and patient-derived (i.e., inflammation, lung function, smoking status, and smoking history) parameters.
Eligibility
Inclusion Criteria3
- Aged 18-65 years
- Compos mentis
- Diagnosed with lung cancer, with treatment requiring a thoracotomy or VATS lobectomy
Exclusion Criteria4
- Neoadjuvant chemo- or radiotherapy in the past four weeks
- Use of systemic steroids in the past four week
- Insulin-dependent diabetes mellitus
- Pregnancy
Interventions
There are no interventions in the present study
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05794529