RecruitingNCT05794529

Lung Tumor Protein Synthesis Rates in Lung Cancer Patients

Characterizing Tissue Protein Synthesis Rates of Non-small Cell Lung Carcinomas in Lung Cancer Patients


Sponsor

Maastricht University Medical Center

Enrollment

30 participants

Start Date

Mar 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The current study will recruit lung cancer patients to measure tissue protein synthesis rates of non-small cell lung carcinomas and healthy lung tissue. The protein synthesis rates of healthy lung tissue will be compared to lung tumor tissue to establish the remodeling characteristics of healthy versus cancerous lung tissues. We will also examine whether tissue protein synthesis rates of non-small cell lung carcinomas are associated with various tumor- (i.e., size, subclassification) and patient-derived (i.e., inflammation, lung function, smoking status, and smoking history) parameters.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria3

  • Aged 18-65 years
  • Compos mentis
  • Diagnosed with lung cancer, with treatment requiring a thoracotomy or VATS lobectomy

Exclusion Criteria4

  • Neoadjuvant chemo- or radiotherapy in the past four weeks
  • Use of systemic steroids in the past four week
  • Insulin-dependent diabetes mellitus
  • Pregnancy

Interventions

OTHERThere are no interventions in the present study

There are no interventions in the present study


Locations(1)

Zuyderland Medical Center

Heerlen, Limburg, Netherlands

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05794529


Related Trials