RecruitingNot ApplicableNCT05832606

Food Intervention to Reduce Immunotherapy ToXicity


Sponsor

Universitair Ziekenhuis Brussel

Enrollment

60 participants

Start Date

Jan 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The FORX (Food intervention to Reduce immunotherapy toXicity) trial will assess whether supplementing dietary fiber intake by providing weekly boxes containing 30 different plants to patients with solid tumors starting immune checkpoint inhibitor therapy affects the incidence of immune related adverse events.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • solid tumor starting anti-programmed cell death protein 1 (anti-PD1) and/or anti-cytotoxic T-lymphocyte-associated antigen 4 (anti-CTLA4) antibodies as part of standard of care.
  • able to sign informed consent.

Exclusion Criteria3

  • no oral intake possible.
  • probiotic use and unwillingness to stop during the trial.
  • combination therapy with chemotherapy or targeted agents.

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Interventions

OTHERFood box containing 30 different plants

Food boxes during first 12 weeks of therapy. Clinical follow-up until end of immunotherapy.


Locations(1)

UZ Brussel

Jette, Belgium

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NCT05832606


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