Fluorescence-guided Resection Of Colorectal Liver Metastases Using SGM-101 and Indocyanine GREEN

This study is testing two fluorescence agents — SGM-101 and indocyanine green (ICG) — to help surgeons see colorectal liver metastases (cancer that has spread from the colon to the liver) more clearly during surgery, using special light-based imaging technology. The goal is to improve how completely these tumors are removed. **You may be eligible if...** - You have confirmed liver metastases from colorectal cancer - You are scheduled for surgical removal of more than 3 liver metastases, OR - You completed chemotherapy (neoadjuvant) within the past 3 months before surgery, OR - You are having a repeat liver surgery for recurrent disease - You are willing and able to give informed consent **You may NOT be eligible if...** - You have an allergy to iodine or iodine-based contrast agents - You are pregnant or breastfeeding - You have serious liver dysfunction beyond what is expected from the metastases - You are not a surgical candidate for liver resection Talk to your doctor to see if this trial is right for you.