RecruitingNot ApplicableNCT05970133

Robotic Versus Laparoscopy NOSE for Stage I-III Left-sided Colon Cancer

Functional Recovery and Oncologic Efficacy of Robotic Versus Laparoscopy NOSE for Patients With Stage I III Left Sided Colon Cancer: A Randomized Controlled Trial


Sponsor

National Taiwan University Hospital

Enrollment

300 participants

Start Date

Apr 7, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

In this project, the investigator aims to provide the level 1 evidence for the comparison of robotic versus laparoscopic NOSE for the surgery of stage I-III colorectal cancer. the investigator hypothesize that, with the increased maneuverability of the current robotic system, robotic surgery will be a good option for patients with stage I-III colorectal cancer requiring a NOSE procedure.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Primary colon cancers located at the left sided colonic anatomic location, including distal transverse colon, colonic splenic flexure, descending colon, sigm oid descending colonic junction, sigmoid colon and upper rectum that required the mobilization of colonic splenic flexure to facilitate a curative resection and trans anal specimen extraction ;
  • TNM Stage I III adenocarcinomas;
  • Curative and elective surgery;
  • American Society of Anesthesiology (ASA) class I to III patients;
  • Age \>18 years.

Exclusion Criteria6

  • Cecal, ascending, the proximal and middle transverse colon cancers; and the middle or lower rectal cancers;
  • Emergency or palliative surgery;
  • Evidence of disseminated disease or adjacent organ invasion;
  • Primary tumor mass \>8 cm in diameter;
  • Morbidly obese patients, that is, body mass index (BMI) ≥40 kg/m 2 ;
  • Previous major surgery of upper abdomen or pelvis

Interventions

PROCEDUREColectomy with NOSE procedure

The specimen will be extract from the anus.


Locations(1)

National Taiwan University Hospital

Taipei, Taiwan

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NCT05970133


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