Tapering of Rituximab Based on Interval Prolongation Compared to Disease Activity-guided Dose Reduction in Patients With Rheumatoid Arthritis

This study compares two approaches for managing rituximab dosing in people with rheumatoid arthritis: stretching out doses over longer intervals versus adjusting doses based on how active the disease is. **You may be eligible if:** - You are 18 or older - You have been diagnosed with rheumatoid arthritis - You are currently being treated with rituximab and have responded well to it - You read and write Dutch or French - You are on a stable dose of methotrexate or another standard arthritis drug **You may NOT be eligible if:** - You are taking another biologic medication (other than rituximab) for arthritis - You are taking a targeted synthetic disease-modifying drug - You are pregnant or wish to become pregnant - You have a reason that rituximab is medically unsafe for you Talk to your doctor to see if this trial is right for you.