Laparoscopic and Endoscopic Collaborative Surgery as Rescue-treatment for Advanced Gastric Cancer
Laparoscopic and Endoscopic Collaborative Surgery as Rescue-treatment for Advanced Gastric Cancer in Patients Unfit for Surgery - the LE-RACUS Pilot Clinical Study
Region Stockholm
20 participants
Apr 17, 2024
INTERVENTIONAL
Conditions
Summary
The standard treatment for advanced gastric cancer without metastases is gastrectomy, where the whole stomach or a large proportion is removed surgically together with regional lymph nodes. Some patients cannot tolerate this invasive procedure because of old age or comorbidities. A tumor left in place can cause local symptoms such as bleeding or outlet obstruction. In this study, the investigators want to test the safety and feasibility of Laparoscopic and Endoscopic Collaborative Surgery (LECS) as a less invasive treatment option to locally remove gastric tumors without requiring extensive surgery in these frail patients. LECS is a minimally invasive surgical technique where the tumor margin is first marked from the inside with a gastroscope, followed by surgical removal of the lesion under endoscopic guidance.
Eligibility
Inclusion Criteria4
- pT2-T4aN0M0 gastric carcinoma
- Borrmann type 1-2 \< 5 cm or Borrmann type 3 \< 2 cm
- Patient assessment by the multidisciplinary tumor board as not fit for gastrectomy
- Signed informed consent
Exclusion Criteria2
- Borrman type 4
- Location in the cardia
Interventions
Minimal invasive surgery in collaboration between endoscopy and laparoscopic surgery, to locally remove the tumor
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06105515