Fluorescence Imaging of Adalimumab-680LT in Inflammatory Bowel Disease

This study uses a specially tagged form of adalimumab (a drug used to treat inflammatory bowel disease) that glows under special imaging light. During an endoscopy, doctors can see exactly where the drug is binding in the gut lining — helping to predict whether a patient will respond to adalimumab therapy before committing to full treatment. **You may be eligible if:** - You have confirmed inflammatory bowel disease (Crohn's disease or ulcerative colitis) - Your disease is currently active (at least mildly) - You are eligible to start adalimumab therapy - You have a clinical reason to undergo an endoscopic procedure - You are 18 or older - You have a negative pregnancy test if applicable **You may NOT be eligible if:** - You have previously received adalimumab or other anti-TNF treatments - You have active serious infections or other major health conditions - You are pregnant or breastfeeding - You have a known allergy to adalimumab Talk to your doctor to see if this trial is right for you.