RecruitingNot ApplicableNCT06151405

Nutrition for Asthmatics

Individualized Nutrition to Help Asthmatics Improve Lung Function and Energetics (INHALE)


Sponsor

Pennington Biomedical Research Center

Enrollment

15 participants

Start Date

Jul 17, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Determine to what extent three distinct dietary approaches improve asthma control and lung function.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria6

  • Age: 18-65 years
  • BMI: 18.5 - 29.99 kg/m2
  • asthma diagnosed by medical specialist (confirmed in medical history)
  • partly controlled or uncontrolled asthma by Asthma Control Test score ≤22
  • owns a device compatible with ZEPHYRx platform
  • stable asthma medication use (no change in the past 2 months).

Exclusion Criteria7

  • Diabetes or using diabetes medications that may lower blood glucose levels
  • point of care fasting blood glucose ≥126 mg/dl or triglycerides ≥400 mg/dl
  • current smoking or smoking history of greater than 10 pack-years
  • other significant respiratory or cardiac disease or the presence of clinically important comorbidities, e.g., COPD, renal failure, liver disease; uncontrolled hypertension defined as systolic blood pressure ≥160 mm/Hg, or diastolic blood pressure ≥100 mm/Hg
  • pregnant or nursing women
  • food preferences or allergies inconsistent with study diet capabilities
  • noncompliance with lead-in period requirements.

Interventions

OTHERDGA Diet

A fully provisioned isocaloric, isonitrogenous study diet following the Dietary Guidelines for Americans (DGA) Including: * A variety of vegetables and fruits * Grains, at least half of which are whole grains * Fat-free or low-fat dairy * A variety of protein foods, including seafood, lean meats and poultry, eggs, legumes, nuts, and seeds * This healthy eating pattern also limits saturated fats and trans fats, added sugars, and sodium.

OTHERMCT Diet

A fully provisioned isocaloric, isonitrogenous study diet following the Dietary Guidelines for Americans supplemented with medium chain triglycerides (MCT).

OTHERKETO Diet

A fully provisioned isocaloric, isonitrogenous ketogenic study diet.


Locations(1)

Pennington Biomedical Research Center

Baton Rouge, Louisiana, United States

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NCT06151405


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