RecruitingNCT06154694

Glenohumeral Joint Contract Patterns in Osteoarthritic Glenoids

In-vivo Evaluation of Glenohumeral Joint Contact Patterns in Osteoarthritic Glenoids


Sponsor

Universitaire Ziekenhuizen KU Leuven

Enrollment

156 participants

Start Date

Nov 3, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

Shoulder osteoarthritis (OA) is a frequent problem in our aging population and is believed to occur in up to 20% of the population. Different types of glenoid morphology are associated with shoulder OA, depending on the amount and localization of the glenoid erosion as well as the amount and direction of Humeral Head Migration. Total shoulder arthroplasty (TSA) has been shown to relieve the pain and improve joint function of patients with OA. However, several complications such as component loosening and polyethylene damage has been reported and it has been revealed that 7.3% of glenoids may show signs of asymptomatic radiographic loosening annually after primary anatomic TSA. The mechanism of such fixation failure is still unclear. The main goal of this study is evaluating in-vivo glenohumeral contact patterns in patients with osteoarthritic glenoids before and after TSA, to unravel the high rate of glenoid component loosening.


Eligibility

Min Age: 18 Years

Inclusion Criteria11

  • OA patients group
  • Patients with glenohumeral osteoarthritis planned for anatomic shoulder arthroplasty in the University Hospitals Leuven, Belgium
  • Complete patient informed consent
  • Pain free at the time of EOS imaging
  • Healthy control group
  • Healthy adult volunteers with no history of shoulder pain or trauma
  • Confirmation of the physician, that subject's clinical evaluation and CT scan did not show any abnormalities
  • Complete informed consent
  • Revised TSA group
  • Patients with glenohumeral osteoarthritis who received an anatomic shoulder arthroplasty at the University Hospitals Leuven within the past 30 years, and who have been revised for loosening of the glenoid component.
  • At least 1 postoperative CT scan available

Exclusion Criteria1

  • Only patients with a functional TSA will be included, so patients with postoperative stiffness, pain, instability or pseudoparalysis will be excluded.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

RADIATIONStereo Radiographic EOS Measurements

Healthy control will undergo a stereo radiographic EOS exam with their arm in various positions. 1. Relaxed standing (0 degree of abduction) 2. 45 degree of abduction in the coronal plane 3. 90 degree of abduction in the coronal plane 4. 120 degree of abduction in the coronal plane 5. 45 degree anterior flexion in the sagittal plane 6. 90 degree anterior flexion in the sagittal plane 7. 120 degree of anterior flexion in the sagittal plane 8. 45 degree extension in the sagittal plane


Locations(1)

UZ Leuven

Leuven, Vlaams-Brabant, Belgium

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06154694


Related Trials