RecruitingNCT06158503

Glycemic Control and Osteohealth in Adults Living With Type 1 Diabetes

GLYcemic COntrol and OSTEOhealth: Impact of Short-Term Glycemic Control on Skeletal Outcomes in Adults With Type 1 Diabetes


Sponsor

Centre hospitalier de l'Université de Montréal (CHUM)

Enrollment

25 participants

Start Date

Feb 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Bone damage is frequently observed in type 1 diabetes, and hyperglycemia is associated with an increased risk of fracture. This pilot study in 25 people living with type 1 diabetes aims to determine whether the introduction of an automated insulin delivery (AID) system improves bone markers through rapide optimization of glycemic control. Measurements will be taken before the start of AID, 2 months and 4 months afterwards.


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at how poor blood sugar control affects bone health in adults with type 1 diabetes. Participants will be starting an automated insulin delivery system (an "artificial pancreas" device) to improve their blood sugar control, and researchers will track whether bone strength and structure improve as a result. **You may be eligible if...** - You are 18 years or older - You have been diagnosed with type 1 diabetes or latent autoimmune diabetes in adults (LADA) for at least one year - Your blood sugar control is currently poor (HbA1c above 8%) with high variability - You are about to start using an automated insulin delivery device - You plan to use this device for the study duration **You may NOT be eligible if...** - You already have well-controlled blood sugar - You are not planning to start an automated insulin delivery device - You have conditions unrelated to diabetes that significantly affect bone health Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEAID

Initiation of an automated insulin delivery system


Locations(2)

CHUM

Montreal, Quebec, Canada

Centre Hospitalier de l'Université de Montréal

Montreal, Canada

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NCT06158503


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