RecruitingNCT06169956

An Observational Study to Evaluate Neoadjuvant Nivolumab (OPDIVO®) in Combination With Platinum-Based Chemotherapy in Non-Metastatic Non-Small Cell Lung Cancer Participants in Germany

Neoadjuvant Nivolumab (OPDIVO®) in Combination With Platinum-Based Chemotherapy for Non-Metastatic NSCLC: A German, Nationwide, Prospective, Observational, Multicenter Study in Patients Scheduled to Receive 3 Cycles Nivolumab in Combination With Platinum-Based Chemotherapy for Non-Metastatic (Stage and PD-L1 Expression According to Label) Non-Small Cell Lung Cancer


Sponsor

Bristol-Myers Squibb

Enrollment

400 participants

Start Date

Nov 30, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this observational study is to collect and evaluate real-world data to assess the effectiveness of neoadjuvant nivolumab when given in combination with platinum-based chemotherapy in participants with early-stage, resectable non-small cell lung cancer (NSCLC) in Germany


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This observational study (no experimental treatment) is following patients in Germany who are receiving nivolumab (an immunotherapy drug) combined with platinum-based chemotherapy before surgery for non-metastatic non-small cell lung cancer, to track real-world outcomes and quality of life. **You may be eligible if...** - You are 18 or older - You have been diagnosed with non-metastatic (not spread to distant organs) non-small cell lung cancer - Your tumor shows PD-L1 expression of at least 1% - Your doctor has already decided (independently of this study) to treat you with nivolumab plus chemotherapy before surgery - You are willing to complete quality-of-life questionnaires in German **You may NOT be eligible if...** - You have another type of cancer currently requiring treatment - You have contraindications to nivolumab based on the drug's approved guidelines Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGNeoadjuvant nivolumab in combination with platinum-based chemotherapy

Neoadjuvant treatment of resectable non-small cell lung cancer with nivolumab in combination with chemotherapy according to current summary of product characteristics


Locations(1)

Klinikverbund Allgaeu

Kempten (Allgäu), Bavaria, Germany

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NCT06169956


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