MRE for Assessment of Histopathological Growth Patterns in Colorectal Liver Metastases
Noninvasive Evaluation in Diagnosis and Treatment of Histopathological Growth Patterns in Colorectal Liver Metastases Using MR Elastography-based Shear Strain Mapping
Shengjing Hospital
50 participants
Dec 24, 2023
OBSERVATIONAL
Conditions
Summary
The goal of this study is to investigate the value of MR elastography-based SII as a means of detecting HGP noninvasively in patients with pathology-proven CRLM. MRE will provide a direct measure of tumor-liver adhesion to investigate the relationship between imaging findings and pathophysiological changes in the Liver.
Eligibility
Inclusion Criteria3
- Diagnosed CRLM
- Pathologic results obtained in surgical patients
- No contraindications for magnetic resonance imaging examination
Exclusion Criteria6
- Image quality does not meet the measurement requirements.
- the diameter of CRLM \<1cm
- Combined with other important organ dysfunction
- Combined with malignant tumor
- Patients who do not sign an informed consent
- Patients with metallic implants or foreign bodies in their bodies (pacemakers, artificial metallic heart valves, metal joints, metal implants, and those who cannot remove dentures, insulin pumps, or contraceptive rings)
Interventions
Assessed boundary conditions through MRE-base SII before surgery and recorded HGP of tumor after surgery.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06208397