Clinical Outcomes of Patients With Coronary Artery Disease
Clinical Outcomes of Patients With Coronary Artery Disease Cohort Study
Shenyang Northern Hospital
10,000 participants
Feb 21, 2024
OBSERVATIONAL
Conditions
Summary
Coronary heart disease (CHD) stands as a foremost contributor to global mortality, characterized by complex pathogenesis that renders conventional "one-size-fits-all" preventive strategies inefficient. Therefore, the investigators designed a prospective, multi-center cohort study among patients hospitalized due to either confirmed or suspected CHD, which aimed to establish a holographic data set for the diagnosis and treatment of CHD and explore the impact of critical therapeutic strategies in the real world on the clinical outcomes of CHD patients, providing evidence to optimize the management pathway.
Eligibility
Inclusion Criteria4
- Age ≥ 18 years old
- Hospitalization due to either confirmed or suspected CHD combined with one of the following features: previous PCI or CABG; previous myocardial infarction; previous coronary angiography revealing ≥ 50% stenosis in major coronary vessels; presentation with chest pain and pre-test probability of CHD \> 65%; laboratory tests revealing objective evidence of myocardial ischemia; coronary CT angiography (CTA) showed ≥ 30% stenosis in major coronary vessels
- Subjects undergoing at least one coronary imaging and one functional examination. Imaging examinations include coronary CTA, intravascular ultrasound (IVUS), or optical coherence tomography (OCT). Functional examination include fraction flow reservation (FFR), CT-FFR or quantitative flow ratio (QFR).
- Written informed consent provided.
Exclusion Criteria5
- History of mental illness, drug or alcohol abuse, or being unable to cooperate with follow-up visits for any reason;
- Life expectancy \<1 year
- Pregnant or plan to be pregnant within 1 year
- Subjects participating in any other clinical trial
- Other conditions deemed unsuitable for inclusion by the investigator
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06216847