RecruitingNot ApplicableNCT06240299

Neurofeedback for Nociplastic Pain in Rheumatoid Arthritis (NECTAR)

Neurofeedback for Nociplastic Pain in Rheumatoid Arthritis


Sponsor

NHS Greater Glasgow and Clyde

Enrollment

16 participants

Start Date

Jun 24, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Rheumatoid arthritis is an autoimmune condition, causing inflammation and pain. Yet pain may persist even when inflammation has been treated. This residual pain, called nociplastic pain, has symptoms of a chronic pain condition called fibromyalgia. There are few effective therapies to address this residual pain. Published literature shows that fibromyalgia can be treated by neurofeedback, a noninvasive method that is based on the voluntary modulation of cortical activity. In this pilot study, the investigators want to test the effect of neurofeedback on the fibromyalgia component of pain in rheumatoid arthritis, and also to investigate its effects on related symptoms such as fatigue and sleep disturbance.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a brain-based treatment called neurofeedback to help people with rheumatoid arthritis who experience widespread, difficult-to-treat chronic pain (called nociplastic pain). Neurofeedback trains people to regulate their own brain activity, which may help reduce pain that does not respond well to standard treatments. **You may be eligible if...** - You have been diagnosed with rheumatoid arthritis - You also meet the criteria for chronic widespread pain - Your arthritis is currently stable (low joint swelling and normal inflammation levels) - Your pain is rated 4 or higher out of 10 - You are right-handed - You have normal or corrected hearing and vision - You can understand English **You may NOT be eligible if...** - You have significant neurological conditions (multiple sclerosis, stroke, Parkinson's, Alzheimer's, or traumatic brain injury) - You have a serious psychiatric condition such as psychosis or active suicidal thoughts - You are currently changing pain medications or receiving another pain treatment - You are enrolled in another interventional study Talk to your doctor to see if this trial is right for you.

This is a simplified summary. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURENeurofeedback

A noninvasive method based on the voluntary modulation of brain activity, with feedback provided through a graphical user interface shown on a computer screen


Locations(1)

Clinical Research Facility (CRF), Queen Elizabeth University Hospital

Glasgow, Scotland, United Kingdom

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NCT06240299


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