RecruitingNot ApplicableNCT06276426

Plants Optimizing Development Study (PODS)

Plants Optimizing Development Study


Sponsor

University of Illinois at Urbana-Champaign

Enrollment

96 participants

Start Date

Mar 18, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to conduct a randomized clinical trial to measure the effects of a 3-month daily mixed-soy food intervention vs. a control group receiving isocaloric foods on reproductive hormones, body composition, metabolic risk, fecal microbiota, and cognition among 8-11-year-old children. Additionally, this study will assess soy food intake immediately following participation in the clinical trial to determine changes in soy food acceptance in children.


Eligibility

Min Age: 8 YearsMax Age: 11 Years

Inclusion Criteria7

  • Child assent and parent/guardian consent
  • Free of any food allergy
  • years of age
  • Tanner scale score of ≤ 2
  • /20 or corrected vision
  • No antibiotic usage in the past 3 months
  • ≤1 serving/d of soy food habitual consumption

Exclusion Criteria9

  • Non-assent or consent by child assent and/or parent/guardian
  • Presence of any food allergy
  • Younger than 8 years or older than 11 years
  • Presence of specific neurological and genetic disorders (i.e., Autism, Cerebral Palsy, Multiple Sclerosis, Down syndrome)
  • Presence of endocrine, metabolic, and gastrointestinal disease e.g., hypertension, diabetes, celiac disease
  • Tanner scale score of \> 2
  • Not 20/20 or uncorrected vision
  • Antibiotic usage in the past 3 months
  • \>1 serving/d of soy food habitual consumption

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Interventions

OTHERSoy foods

Soy milk, soy yogurt, tofu, tempeh, soy nuts, edamame, soy protein bar, and soy-based frozen meat substitutes.

OTHERNon-Soy Plant-Based Foods

Pea milk, almond milk yogurt, chickpeas, chickpea chips, lentil chips, non-soy protein bar, and non-soy based frozen meat substitutes.


Locations(1)

University of Illinois

Urbana, Illinois, United States

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NCT06276426


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