RecruitingPhase 4NCT06298461

Bowel Preparation for Colonoscopy Among Individuals With Crohn's and Ulcerative Colitis Disease.

Bowel Preparation for Colonoscopy Among Individuals With IBD: A Randomized Controlled Trial


Sponsor

University of Manitoba

Enrollment

418 participants

Start Date

Jul 4, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to compare how effective and how tolerable two different bowel preparation laxatives are for colonoscopy. The aim is to compare oral sulfate solution (OSS) to another laxative called 2L polyethylene glycol (PEG) solution to see which is more effective and more tolerable by individuals with IBD (Crohn's disease or Ulcerative colitis).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study compares two bowel preparation products — a standard large-volume solution (PEG) and a lower-volume oral sulfate solution — in people with Crohn's disease or ulcerative colitis who need to prepare for a colonoscopy. **You may be eligible if...** - You are 18 or older with Crohn's disease or ulcerative colitis - You are scheduled for (or about to be scheduled for) a colonoscopy - You are an outpatient (not currently admitted to hospital) **You may NOT be eligible if...** - You have had most or all of your large bowel surgically removed - You have kidney insufficiency, heart failure, cirrhosis, or severe electrolyte imbalance that makes bowel prep risky - You had a colonoscopy in the past 6 months that had to be redone due to poor bowel preparation - You are allergic to either of the prep solutions used in the study - You have toxic megacolon, bowel obstruction, or are too sick to undergo colonoscopy - You are currently hospitalized with severe IBD - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGKleanLyte

Laxative for colonoscopy bowel preparation

DRUGBi-PegLyte

Laxative for colonoscopy bowel preparation


Locations(1)

University of Manitoba

Winnipeg, Manitoba, Canada

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NCT06298461


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