RecruitingPhase 4NCT06298461

Bowel Preparation for Colonoscopy Among Individuals With Crohn's and Ulcerative Colitis Disease.

Bowel Preparation for Colonoscopy Among Individuals With IBD: A Randomized Controlled Trial

Sponsor

University of Manitoba

Enrollment

418 participants

Start Date

Jul 4, 2024

Study Type

INTERVENTIONAL

Conditions

Crohn Disease Ulcerative Colitis

Summary

The purpose of this study is to compare how effective and how tolerable two different bowel preparation laxatives are for colonoscopy. The aim is to compare oral sulfate solution (OSS) to another laxative called 2L polyethylene glycol (PEG) solution to see which is more effective and more tolerable by individuals with IBD (Crohn's disease or Ulcerative colitis).

Eligibility

Min Age: 18 Years

Inclusion Criteria3

Crohn's disease or ulcerative colitis patients scheduled or about to be scheduled for colonoscopy.
Age \> 18 years
Out-patients

Exclusion Criteria7

Prior subtotal or total colorectal resection
Contraindications to use of 2L polyethylene glycol (2L-PEG) or Oral Sulfate Solution (OSS): Known renal insufficiency, congestive heart failure, cirrhosis, severe electrolyte imbalance.
Colonoscopy being repeated because of poor preparation in the preceding six months.
Allergies to the employed bowel preparations
Toxic megacolon, ileus, suspected or diagnosed bowel obstruction.
IBD patients thought to be too sick to undergo a full colonoscopy preparation in the opinion of the investigator/treating physician; hospitalized crohn's disease or ulcerative colitis patients.
Pregnancy