RecruitingNot ApplicableNCT06306651

High Flow Nasal Cannula and Conventional Oxygen Therapy in the Postoperative Management of Patients With Mild to Moderate Obstructive Sleep Apnea

Comparative Study Between High Flow Nasal Cannula and Conventional Oxygen Therapy in the Postoperative Management of Patients With Mild to Moderate Obstructive Sleep Apnea


Sponsor

Ain Shams University

Enrollment

60 participants

Start Date

Mar 16, 2024

Study Type

INTERVENTIONAL

Summary

This study aims to compare the effectiveness of conventional oxygen therapy oxygen and high-flow nasal cannula therapy on oxygen saturation (SpO2), measuring number of SpO2 drop \>4% of base line oxygen saturation (o2 desaturation index), length of the ICU stay, and the need of use supplemental continuous positive airway pressure (CPAP) support in any of the study groups in the postoperative ICU setting.


Eligibility

Min Age: 21 YearsMax Age: 40 Years

Inclusion Criteria5

  • Age group from 21 - 40 years old.
  • Both sexes.
  • Mild to moderate obstructive sleep apnea (OSA) patients with STOP-BANG score less than 5.
  • OSA patients undergoing non cardiac surgeries.
  • Patients who will undergo scheduled elective surgeries under general anesthesia.

Exclusion Criteria7

  • Patient refusal of procedure or participation in the study.
  • Patients with severe OSA, STOP-BANG score more than or equal 5.
  • Patients dependent on home ventilation CPAP or bilevel devices.
  • Pregnant females.
  • Post cardiac or thoracic surgery patients.
  • More than American Society of Anesthesiologists (ASA) II patients.
  • Head and face trauma patients.

Interventions

OTHERHigh flow nasal cannula therapy group

Patients who will be randomized to high flow nasal cannula therapy. High flow nasal oxygen cannula will be applied at a flow of 20 L/min at FiO2 of 0.4 at a temperature of 36oC

OTHERConventional oxygen therapy group

Patients who will be randomized to simple oxygen mask therapy. The simple face mask will be applied in a rate range between 6-10 L/min.


Locations(1)

Ain Shams University

Cairo, Egypt

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NCT06306651