RecruitingNCT06314113

Evaluation of Oral EGCG Treatment for L-SIL Associated With HPV Infection

Evaluation of Oral Epigallocatechin Gallate Treatment for Low-grade Cervical Lesions (L-SIL) Associated With Human Papilloma Virus (HPV) Infection


Sponsor

University of Palermo

Enrollment

50 participants

Start Date

Mar 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The study aims to evaluate the effectiveness of the synergy of oral Epigallocatechin Gallate as a treatment for Low-grade Cervical Lesions (L-SIL) associated with Human Papilloma Virus (HPV) infection.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether an oral supplement called EGCG (epigallocatechin gallate — a compound found in green tea) can help treat low-grade cervical cell changes (L-SIL) caused by HPV infection. The hope is that EGCG's antiviral and immune-supporting properties might help clear the infection and reverse the abnormal cells. **You may be eligible if...** - You are a woman who has been diagnosed with low-grade squamous intraepithelial lesions (L-SIL) of the cervix - Your L-SIL is associated with confirmed HPV infection **You may NOT be eligible if...** - You are pregnant - You have a condition or take medications that suppress your immune system - You are on hormone replacement therapy - You have been diagnosed with high-grade cervical lesions (H-SIL) or adenocarcinoma in situ - You have a history of cervical lesions (L-SIL or worse) within the past 24 months Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTEpigallocatechin Gallate

Oral treatment with Epigallocatechin Gallate 200 mg per day


Locations(1)

"Paolo Giaccone" Hospital

Palermo, Italy

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NCT06314113