RecruitingNCT06314113

Evaluation of Oral EGCG Treatment for L-SIL Associated With HPV Infection

Evaluation of Oral Epigallocatechin Gallate Treatment for Low-grade Cervical Lesions (L-SIL) Associated With Human Papilloma Virus (HPV) Infection


Sponsor

University of Palermo

Enrollment

50 participants

Start Date

Mar 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The study aims to evaluate the effectiveness of the synergy of oral Epigallocatechin Gallate as a treatment for Low-grade Cervical Lesions (L-SIL) associated with Human Papilloma Virus (HPV) infection.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 65 Years

Inclusion Criteria1

  • Women affected by Low-grade Cervical Lesions (L-SIL) associated with Human Papilloma Virus (HPV) Infection

Exclusion Criteria6

  • Pregnancy
  • Concomitant pathologies causing immunosuppression
  • Concurrent Immunomodulatory therapies
  • Hormone replacement therapy
  • High-grade Cervical Lesions (H-SIL) or in situ adenocarcinoma
  • Previous history of L-SIL or higher grade lesions ≥ 24 months

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Interventions

DIETARY_SUPPLEMENTEpigallocatechin Gallate

Oral treatment with Epigallocatechin Gallate 200 mg per day


Locations(1)

"Paolo Giaccone" Hospital

Palermo, Italy

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NCT06314113