RecruitingNot ApplicableNCT06321133

High Flow Nasal Cannula Weaning in Acute Bronchiolitis

High Flow Nasal Cannula Weaning in Acute Bronchiolitis - an Open-label Randomized Controlled Trials


Sponsor

Kuopio University Hospital

Enrollment

50 participants

Start Date

Feb 13, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical study is to compared two different strategies to end high flow nasal cannula treatment in acute bronchiolitis. This study compared the immediate ending of high flow treatment to weaning strategy, in which the flow rate is gradually decreased. The aim is to assess if the immediate ending shortens the hospitalization time and whether it is a safe strategy.


Eligibility

Min Age: 0 MonthsMax Age: 12 Months

Inclusion Criteria5

  • Clinically diagnosed acute bronchiolitis
  • High flow nasal cannula treatment has lasted for at least 12 hours
  • Measured saturation 95 or more with room air
  • High flow rate is maximum 2l/kg/min
  • The treating doctors considers the infant suitable to be without high flow

Exclusion Criteria3

  • Major congenital anomaly of lungs, hearts or diaphragm
  • Bacterial pneumonia
  • Parents do not give consent

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Interventions

OTHERHigh flow nasal cannula immediate ending

High flow is immediately ended

OTHERHigh flow nasal cannula weaning

High flow is gradually weaned by reducing the flow rate


Locations(4)

Siun Sote

Joensuu, Finland

Central Finland Hospital District

Jyväskylä, Finland

Kuopio University Hospital

Kuopio, Finland

Mikkeli Central Hospital

Mikkeli, Finland

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NCT06321133


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