RecruitingNot ApplicableNCT06359964

Infective Complications in TP Biopsy Without Antibiotic Prophylaxis

Infective Complications in Transperineal Prostate Biopsy Without Antibiotic Prophylaxis: A Prospective Cohort Study

Sponsor

Chinese University of Hong Kong

Enrollment

1,900 participants

Start Date

Aug 4, 2024

Study Type

INTERVENTIONAL

Conditions

Prostate Cancer

Summary

This study is a prospective cohort study to delineate the infective outcomes and incidence after transperineal prostate biopsy with no antibiotic prophylaxis, compared to the existing data on outcomes on patients receiving transperineal prostate biopsy with antibiotic prophylaxis.

Eligibility

Sex: MALEMin Age: 18 Years

Inclusion Criteria7

All consecutive patients in participating centres receiving transperineal USG-guided biopsy for any indication including:
Elevated PSA
Abnormal DRE
Follow-up biopsy in active surveillance
Suspicion of CAP recurrence after radiotherapy
Follow-up biopsy after focal therapy
Consenting to the study

Exclusion Criteria7

Recent suspected UTI within 1 month
Recent culture proven bacteriuria within 1 month
History of recurrent UTI
Indwelling urinary catheter
Immunocompromised state
High risk of infective endocarditis (including prosthetic heart valve, congenital heart disease, or previous history of infective endocarditis
Incompetent or incapable of understanding the nature of the study or giving informed consent