RecruitingNCT06366828

Prediction Models for Complications After CRT in Esophageal Cancer


Sponsor

University Medical Center Groningen

Enrollment

2,000 participants

Start Date

Feb 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of this project is to develop and validate NTCP-models for complications after nCRT (and surgical resection), that can be uses for model-based dose optimization for PhRT and PRT, and for model-based selection for PRT, in patients with esophageal cancer


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria5

  • Tumor in the esophagus, histologically proven or suspect for esophageal carcinoma
  • WHO performance 0-2
  • Age\>18years
  • No distant metastasis (M0)
  • Treated with nCRT and planned for or followed by an esophagectomy between 2015 and 2021 in one of the participating centers.

Exclusion Criteria2

  • Sarcoma, neuro-endocrine or small cell carcinoma of the esophagus
  • Patients who underwent a surgical resection in a non-participating surgical center will be excluded

Interventions

OTHERretrospective

follow up


Locations(8)

Radboud UMC

Nijmegen, Gelderland, Netherlands

Maastro clinic

Maastricht, Limburg, Netherlands

Amsterdam UMC

Amsterdam, North Holland, Netherlands

Erasmus MC

Rotterdam, South Holland, Netherlands

Holland PTC

Delft, Netherlands

UMCG

Groningen, Netherlands

Zuyderland hospital

Heerlen, Netherlands

UMCU

Utrecht, Netherlands

View Full Details on ClinicalTrials.gov

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NCT06366828