RecruitingNCT06366828

Prediction Models for Complications After CRT in Esophageal Cancer


Sponsor

University Medical Center Groningen

Enrollment

2,000 participants

Start Date

Feb 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of this project is to develop and validate NTCP-models for complications after nCRT (and surgical resection), that can be uses for model-based dose optimization for PhRT and PRT, and for model-based selection for PRT, in patients with esophageal cancer


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This study is building prediction models to identify which patients with esophageal cancer are most likely to develop complications after receiving chemoradiation followed by surgery, using data from past patient records. **You may be eligible if...** - You have a confirmed or suspected esophageal cancer diagnosis - You have a WHO performance status of 0–2 (able to carry out daily activities) - You are 18 or older - You have no distant spread of cancer (M0 stage) - You were treated with chemotherapy plus radiation and then had esophageal surgery between 2015 and 2021 at one of the participating centers **You may NOT be eligible if...** - Your cancer type is sarcoma, neuroendocrine, or small cell carcinoma of the esophagus - Relevant medical records are unavailable Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERretrospective

follow up


Locations(8)

Radboud UMC

Nijmegen, Gelderland, Netherlands

Maastro clinic

Maastricht, Limburg, Netherlands

Amsterdam UMC

Amsterdam, North Holland, Netherlands

Erasmus MC

Rotterdam, South Holland, Netherlands

Holland PTC

Delft, Netherlands

UMCG

Groningen, Netherlands

Zuyderland hospital

Heerlen, Netherlands

UMCU

Utrecht, Netherlands

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NCT06366828