RecruitingNCT06380855

Flexible Colonoscope Assisted Hybrid Transanal Total Mesorectal Resection (taTME)


Sponsor

Sun Yat-sen University

Enrollment

5 participants

Start Date

Aug 24, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The investigators propose to use flexible endoscopy combined with transanal total mesorectal resection to further reduce anal injury.


Eligibility

Inclusion Criteria4

  • Age between 18 and 80 years old
  • Confirmed rectal adenocarcinoma cancer pathologically
  • tumor location ≦ 12 cm from the anal margin
  • Willing and able to provide written informed consent for participation in this study

Exclusion Criteria7

  • distant metastasis before surgery
  • more than one colorectal tumor at diagnosis
  • familial adenomatous polyposis
  • recurrent rectal cancer
  • undergo transanal minimally invasive surgery
  • undergo palliative treatment
  • undergo emergency surgery

Interventions

PROCEDUREFlexible colonoscope assisted hybrid transanal total mesorectal resection

Endoscopic pursestring suture (EPSS) was performed at the distance from 1cm to the inferior edge of the tumor by a double-channel flexible colonoscope. An endoloop was inserted through one channel. Meanwhile, the endoclips was inserted through the other channel one by one to fix the endoloop around the rectal wall. And then the endoloop was tightened slowly. After completing the routine lavage lumen, a full-thickness, circumferential dissection was performed by flexible colonoscope following taTME surgical principle until it converged with the laparoscopy group.


Locations(1)

Department of colorectal surgery, the Sixth Affiliated Hospital, Sun Yat-Sen University

Guangzhou, Guangdong, China

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NCT06380855


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