RecruitingNot ApplicableNCT06393907

Hemostatic Forceps vs. Bipolar Electrocautery Probes for High-Risk Bleeding Gastroduodenal Ulcers

A Randomized Trial of Hemostatic Forceps Versus Bipolar Electrocautery Probes for High-Risk Bleeding Gastroduodenal Ulcers


Sponsor

Mahidol University

Enrollment

150 participants

Start Date

Mar 26, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

A randomized controlled trial to evaluate the efficacy of hemostatic forceps and bipolar electrocautery probes in patient with high risk bleeding gastroduodenal ulcers.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • The patient with upper gastrointestinal hemorrhage age ≥ 18 years old
  • The patient with gastroduodenal ulcer with indication for hemostatic intervention including 2.1 Forrest classification 1a (Active spurting) 2.2 Forrest classification 1b (Active oozing) 2.3 Forrest classification 2a (Non-bleeding visible vessel; NBVV) 2.4 Forrest classification 2b (Adherent clot) with lesion underneath clot which need hemostatic intervention including active spurting, active oozing or non-bleeding visible vessel

Exclusion Criteria7

  • Uncorrectable hemostasis laboratory including serum platelet \< 50000 /mm3 or International Normalized Ratio (INR) \>1.5
  • Bleeding from cancerous gastroduodenal ulcer
  • The patient with history of gastric surgery
  • The patient with history of bleeding gastroduodenal ulcer within 30 days prior to enrollment
  • The patient with history of proton pump inhibitor allergy
  • Pregnant
  • The patient deny to participate in the study

Interventions

DEVICEHemostatic Forceps

The experimental device will be used for control bleeding in high risk gastroduodenal ulcers.

DEVICEBipolar Electrocautery Probes

The active comparator devices will be used for control bleeding in high risk gastroduodenal ulcers.


Locations(1)

Faculty of internal medicine siriraj hospital, Mahidol university

Bangkok Noi, Bangkok, Thailand

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NCT06393907