RecruitingNot ApplicableNCT06433063

Effect of Hypoxia on FMISO PET to Response to Lu-177 PSMA Treatment

Effect of 18F-Fluoromisonidazole (18F-FMISO) PET Imaging on Evaluation of Hypoxia Before Lu-177 PSMA Treatment for Prostate Cancer


Sponsor

Cigdem Soydal

Enrollment

30 participants

Start Date

Feb 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

It is aimed to evaluate hypoxia before Lu-177 PSMA treatment in prostate cancer and to show its effect on treatment success with 18F-FMISO PET imaging, which allows in-vivo evaluation and quantification of tumor hypoxia, which is known to be one of the factors affecting radiotherapy resistance.


Eligibility

Sex: MALEMin Age: 18 Years

Inclusion Criteria2

  • over 18 years old
  • Patients diagnosed with prostate cancer who were referred to our clinic for Lu-177 PSMA treatment and were found suitable for treatment

Exclusion Criteria3

  • Has a life expectancy of less than 3 months
  • ECOG\>2
  • contraindication for radionuclide treatment with Lu-177 PSMA

Interventions

DIAGNOSTIC_TESTF-MISO PET

Evaluation of tumor hypoxia with F-MISO PET


Locations(1)

Ankara University Medical School

Ankara, Turkey (Türkiye)

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NCT06433063


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