Effect of Ketalar or Dexmedetomidine on Increased Sensitivity to Pain Following Treatment With Remifentanil
Comparison of the Effect of Ketalar or Dexmedetomidine on Increased Sensitivity to Pain Induced Following Treatment With Remifentanil in Patients Undergoing a Laparoscopic Cholecystectomy
Assaf-Harofeh Medical Center
90 participants
Apr 18, 2024
INTERVENTIONAL
Conditions
Summary
Analgesia is one of the pillars of anesthesia. One of the common opiates for pain relief, with a short half-life, is Remifentanil. However, following Remifentanil treatment an increased sensitivity to pain \[hyperalgesia\] appears. The aim of the study is to compare the effects between complementary treatments, like Ketalar and Dexmedetomidine, in preventing increased sensitivity to pain after Remifentanil treatment
Eligibility
Inclusion Criteria1
- • Patients who are about to undergo alaparoscopic cholecystectomy under general anesthesia
Exclusion Criteria8
- Patients with sensitivity to the anesthetic
- Patients with chronic pain who are in regular treatment
- Urgent surgery
- Patients with ischemic heart disease
- Patients with known bradycardia
- Patients with a pacemaker
- Prolonged use of opiates
- Kidney/liver function problems
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
a dissociative anesthetic used medically for induction and maintenance of anesthesia
an agonist of α2-adrenergic receptors in certain parts of the brain used for sedation
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06473896