Effect of Ketalar or Dexmedetomidine on Increased Sensitivity to Pain Following Treatment With Remifentanil
Comparison of the Effect of Ketalar or Dexmedetomidine on Increased Sensitivity to Pain Induced Following Treatment With Remifentanil in Patients Undergoing a Laparoscopic Cholecystectomy
Assaf-Harofeh Medical Center
90 participants
Apr 18, 2024
INTERVENTIONAL
Conditions
Summary
Analgesia is one of the pillars of anesthesia. One of the common opiates for pain relief, with a short half-life, is Remifentanil. However, following Remifentanil treatment an increased sensitivity to pain \[hyperalgesia\] appears. The aim of the study is to compare the effects between complementary treatments, like Ketalar and Dexmedetomidine, in preventing increased sensitivity to pain after Remifentanil treatment
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
a dissociative anesthetic used medically for induction and maintenance of anesthesia
an agonist of α2-adrenergic receptors in certain parts of the brain used for sedation
Locations(1)
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NCT06473896