RecruitingNot ApplicableNCT06521541

Whole Course Multi-model Prehabilitation to Improve Clinical Outcome in Patients Undergoing Neoadjuvant Treatment Prior to Gastrectomy

Whole Course Multi-model Prehabilitation to Improve Clinical Outcome in Patients Undergoing Neoadjuvant Treatment Prior to Gastrectomy : A Single Center Randomized Control Trial

Sponsor

The Affiliated Hospital of Qingdao University

Enrollment

90 participants

Start Date

Jun 1, 2024

Study Type

INTERVENTIONAL

Conditions

Gastric Cancer Prehabilitation

Summary

The intention of research is to establish a multimodal prehabilitation protocol in patients who undergo neoadjuvant chemotherapy prior to gastrectomy, explore the feasibility and effectiveness of the measures and evaluate the effect of program on short-term clinical outcome, fitness and long-term prognosis.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing whether a structured exercise and rehabilitation program (called prehabilitation) started before and continued during chemotherapy can improve outcomes for patients with stomach cancer who will have surgery after receiving neoadjuvant (pre-surgery) chemotherapy. **You may be eligible if...** - You are 18 or older - You have been diagnosed with stomach (gastric) adenocarcinoma confirmed by biopsy - Your medical team has recommended pre-surgery chemotherapy (neoadjuvant therapy) followed by surgery - You have normal heart, lung, liver, and kidney function - You are in reasonably good health (ECOG score 2 or lower) - You are not pregnant or breastfeeding **You may NOT be eligible if...** - The cancer has spread to other organs (metastatic disease) - You have severe heart failure, advanced liver disease (Child-Pugh C), end-stage kidney failure, or very high surgical risk - You had a stroke, brain bleed, or serious neurological/psychiatric condition in the past 6 months - You have a severe active infection or allergy to chemotherapy drugs - You are enrolled in another clinical trial Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALMultimodal prehabilitation program

Patients adopted planned, structural, repetitive and purposeful approach that includes elements of exercise, nutritional and psychological.Patients were evaluated for changes during neoadjuvant therapy and postoperative recovery

BEHAVIORALERAS program

The core content is to adopt a series of optimized measures performed during the perioperative period on the basis of evidence-based medical findings to reduce the physiological and psychological stress of patients and to accelerate their recovery.