RecruitingNCT06556797

Proof-of-concept Study on Dyspnea Analysis Via GapCO2

How to Differentiate Congestive and Non-congestive Dyspnea in the Emergency Department? Proof-of-concept Study on Microperfusion Analysis Via GapCO2

Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

45 participants

Start Date

Jan 26, 2025

Study Type

OBSERVATIONAL

Conditions

Dyspnea Acute Dyspnea

Summary

Patients presenting to the emergency department with acute dyspnea undergo arterial blood gas measurement and monitoring of transcutaneous capnography using the TCM5 monitor. The aim of this study is to determine whether GapCO2, the difference between transcutaneous and arterial pCO2 (PaCO2 - PtcCO2), is correlated with the congestive or non-congestive origin of dyspnea.

Eligibility

Min Age: 18 Years

Inclusion Criteria5

Age ≥ 18 years
Patient presenting with acute dyspnea defined by a sensation of respiratory discomfort with at least one of the following criteria: RR ≥ 22 and/or SpO2 \< 95%
Arterial blood gas sampling performed as part of care
Inclusion less than 1 hour after arrival time to the emergency department
Non-opposition to participation in the study

Exclusion Criteria4

Temperature greater than or equal to 37.5°C
Patient who has already received a diuretic or vasodilator treatment in the emergency department or by a prehospital medical team
Systolic blood pressure less than or equal to 100 mmHg and/or signs of peripheral hypoperfusion
Inability to express refusal to participate in the study

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