An Observational Study of Predictors and Outcomes of Lung Cancer in Never-smokers in the UK
University College London Hospitals
225 participants
Sep 17, 2024
OBSERVATIONAL
Conditions
Summary
The goal of this observational study is to improve the early detection of lung cancer in adults who have smoked less than 100 tobacco cigarettes ("never-smokers") in the United Kingdom. The main questions it aims to answer are: * To describe characteristics such as demographics, co-morbidities and environmental exposures * To describe participant pathways including presentation mode and symptoms to understand if earlier diagnosis would be possible * To describe participant outcomes such as cancer stage, treatment and mortality * To quantitatively or qualitatively measure modifiable and non-modifiable factors that may be associated with LCINS including environmental measures, blood tests and genomic data. Participants will currently have no change to their usual care.
Eligibility
Inclusion Criteria1
- All adult participants from age of 18 who are diagnosed or treated with primary lung cancer through radiology or histology at any participating study site
Exclusion Criteria4
- Participants who have ever smoked cigarettes or tobacco will be excluded; this is defined as:
- More than 100 cigarettes or 75g tobacco in their lifetime
- Those who have received a prescription for nicotine replacement therapy
- For prospective participants, those who cannot consent will be excluded
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06575439