RecruitingNot ApplicableNCT06590623
The Effect of Acute Exogenous Oral Ketone Supplementation on Immune Cells Function and Immune Cells Histone Β-hydroxybutyrylation
Sponsor
University of British Columbia
Enrollment
12 participants
Start Date
Oct 1, 2024
Study Type
INTERVENTIONAL
Conditions
Summary
To conduct a single-arm pilot study to determine how acute ingestion of an exogenous ketone monoester supplement alters the histone lysine β-hydroxybutyrylation and immune function in healthy human monocytes and lymphocytes.
Eligibility
Min Age: 19 Years
Inclusion Criteria2
- Over the age of 19
- Able to fast overnight
Exclusion Criteria6
- Being a competitive endurance athlete.
- Following a ketogenic diet, low-calorie diet, periodic fasting regimen, or regularly consuming ketogenic supplements.
- Being unable to travel to and from the university
- Being pregnant.
- Having been diagnosed with a chronic disorder of glucose or fat metabolism, including type 2 diabetes, chronic pancreatitis, or gallbladder disease
- Being unable to read or communicate in English.
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Interventions
DIETARY_SUPPLEMENTKetone Monoester (KE)
Participants will receive an exogenous ketone supplement (KetoneAid KE4) in a fasted state in the morning, at a dosage of 0.75 g/kg of body weight.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06590623