Study Evaluating AZD7798 for Treatment in Crohn's Disease Patients With an Ileostomy

This study tests a new drug (AZD7798) applied directly into the intestine through an ileostomy (a surgical opening on the abdomen) in people with active Crohn's disease affecting the small intestine. The goal is to reduce intestinal inflammation with fewer whole-body side effects. **You may be eligible if...** - You are between 18 and 80 years old - You have a confirmed diagnosis of Crohn's disease with active inflammation in your small intestine - You have had an ileostomy for at least 3 months - A recent scope of your small intestine confirms active disease **You may NOT be eligible if...** - Your Crohn's disease involves only the large intestine (colon) - You have had recent bowel surgery or major complications - You have serious infections or significant other health conditions that could interfere with the study Talk to your doctor to see if this trial is right for you.